Tag Archives: makrani

HGDP

Human Genome Diversity Project (HGDP) is the best resource for a diverse set of genomic data. It has 1050 individuals from 52 different populations.

I got the Stanford University data which has data for 660,918 SNPs from 1,043 samples. It is claimed that the forward strand is given but that turned out not to be true and I had to flip strands and make sure I didn't include any ambiguous A/T or C/G strands in my dataset.

I followed the recommendations of Rosenberg (spreadsheet) in excluding some atypical samples and relatives, leaving me with 940 samples.

I also excluded the Native American samples because we are not interested in them and they are very closely related either due to recent endogamy or ancient bottlenecks. (yeah I had the nerve to write that.)

Of the total of 876 samples, here are the numbers for our populations of interest:

Balochi 24
Brahui 25
Burusho 25
Hazara 22
Kalash 23
Makrani 25
Pathan 22
Sindhi 24
Total South Asians 190

These samples have about 541,560 SNPs in common with 23andme v2.